兰文智

南京大学生命科学学院教授

兰文智，毕业于美国加州大学，博士，南京大学生命科学学院教授。

人物经历

2003-2006年：加拿大皇后大学(Queen’s University)，博士后。

2006-2011年：美国加州大学伯克利分校(University of California at Berkeley)，博士后、Associate Specialist。

2011年10月-今：南京大学生命科学学院教授。

2012年-今：南京大学博士生导师。

研究方向

营养分配和植物生长发育;植物营养稳态与逆境胁迫

研究内容：

生命活动依赖于物质的有效分配。植物利用各种膜(质膜和内膜)定位的转运体蛋白将营养物质(养分)运送到特定的细胞空间，优化有限养分的利用，保障正常/逆境条件下生长发育的需要。本课题组主要利用分子生物学、生物物理学、组织化学、蛋白荧光标记和分子遗传学等方法，探讨植物协调物质分配的分子机理;侧重于鉴定关键膜系统蛋白组分及其信号转导过程，为分子培育优质作物提供新基因和新理论。

获奖情况

1. 第二届江苏省特聘教授。

2. 2017年度“南京大学优秀博士论文”和2017年度“江苏省优秀博士论文优秀博士论文”指导教师。

3. 湖北省2006年度科学技术三等奖(编号2006Z-033-3-015-012)。

科研成果

Selected：(*，第一作者;#，通讯作者)

Jing Y*, Zheng X*, Zhang D, Shen N, Wang Y, Yang L, Fu A, Shi J, Zhao F, Lan W#, Luan S#. Danger-Associated Peptides Interact with PIN-Dependent Local Auxin Distribution to Inhibit Root Growth in Arabidopsis. Plant Cell. 2019 Aug;31(8):1767-1787. doi: 10.1105/tpc.18.00757. (第一作者：荆彦平博士生/郑小江博士后) 。

Luan M*, Lan W#. Escape routes for vacuolar phosphate. Nat Plants. 2019 Jan;5(1):9-10. doi: 10.1038/s41477-018-0343-2. (Invited Comment) (第一作者：栾明达博士生)。

Zhang F*, Yan X, Han X, Tang R, Chu M, Yang Y, Yang YH, Zhao F, Fu A, Luan S#, Lan W#. A Defective Vacuolar Proton Pump Enhances Aluminum Tolerance by Reducing Vacuole Sequestration of Organic Acids. Plant Physiol. 2019 Oct;181(2):743-761. doi: 10.1104/pp.19.00626(第一作者：张丰博士生)。

Luan M*, Zhao F, Han X, Sun G, Yang Y, Liu J, Shi J, Fu A, Lan W#, Luan S#. Vacuolar phosphate transporters contribute to systemic phosphate homeostasis vital for reproductive development in Arabidopsis. Plant Physiol.2019 Feb;179(2):640-655. doi: 10.1104/pp.18.01424. (第一作者：栾明达博士生) 。

Zhang B*, Zhang C*, Liu C, Jing Y, Wang Y, Jin L, Yang L, Fu A, Shi J, Zhao F, Lan W#, Luan S#. Inner Envelope CHLOROPLAST MANGANESE TRANSPORTER 1 Supports Manganese Homeostasis and Phototrophic Growth in Arabidopsis. Mol Plant. 2018 Jul 2;11(7):943-954. doi: 10.1016/j.molp.2018.04.007. Epub 2018 May 5. Mol Plant. (第一作者：张斌博士生/张弛博士生) 。

Zheng X*, Kang S*, Jing Y, Ren Z, Li L, Zhou JM, Berkowitz G, Shi J, Fu A, Lan W, Zhao F#, Luan S#. Danger-Associated Peptides Close Stomata by OST1-Independent Activation of Anion Channels in Guard Cells. Plant Cell. 2018 May;30(5):1132-1146. doi: 10.1105/tpc.17.00701. Epub 2018 Apr 30. (第一作者：郑小江博士后/韩国KAIST Kang博士后) 。

Luan M*, Liu J*, Liu Y, Han X, Sun G, Lan W#, Luan S#. Vacuolar Phosphate Transporter 1 (VPT1) Affects Arsenate Tolerance by Regulating Phosphate Homeostasis in Arabidopsis. Plant Cell Physiol. 2018 Feb 6. doi: 10.1093/pcp/pcy025. (第一作者：栾明达博士生/刘金隆博士生)。

Wang Y*, Yang L*, Tang Y, Tang R, Jing Y, Zhang C, Zhang B, Li X, Cui Y, Zhang C, Shi J, Zhao F, Lan W#, Luan S#. Arabidopsis choline transporter-like 1 (CTL1) regulates secretory trafficking of auxin transporters to control seedling growth. PLoS Biol. 2017 Dec 28;15(12):e2004310. (第一作者：王愿博士生/杨磊副研究员)。

Luan M*, Tang RJ, Tang Y, Tian W, Hou C, Zhao F, Lan W#, Luan S#. Transport and homeostasis of potassium and phosphate: limiting factors for sustainable crop production. J Exp Bot. 2017 Jun 1;68(12):3091-3105. (第一作者：栾明达博士生)。

Chen J, Yu F#, Liu Y, Du C, Li X, Zhu S, Wang X, Lan W, Rodriguez PL, Liu X, Li D, Chen L#, Luan S#. FERONIA interacts with ABI2-type phosphatases to facilitate signaling cross-talk between abscisic acid and RALF peptide in Arabidopsis. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5519-27. doi: 10.1073/pnas.1608449113.

Liu J*, Yang L, Luan M, Wang Y, Zhang C, Zhang B, Shi J, Zhao FG#, Lan W#, Luan S# (2015) A vacuolar phosphate transporter essential for phosphate homeostasis in Arabidopsis. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6571-8. (第一作者：刘金隆博士生)。

Zhou L*, Lan W*, Chen B, Fang W, Luan S#. A calcium sensor-regulated protein kinase, CALCINEURIN B-LIKE PROTEIN-INTERACTING PROTEIN KINASE19, is required for pollen tube growth and polarity. Plant Physiol 2015 Apr;167(4):1351-60.

Zhou L*, Lan W*, Jiang Y, Fang W, Luan S#(2014) A calcium-dependent protein kinase interacts with and activates a calcium channel to regulate pollen tube growth. Mol Plant 7(2):369-76.

Lee SC*, Lim CW*, Lan W*, He K, Luan S#, (2013). ABA Signaling in Guard Cells Entails a Dynamic Protein-Protein Interaction Relay from the PYL-RCAR Family Receptors to Ion Channels. Mol Plant, 6(2):528-538.

Lan WZ *, Lee SC*, She YF, Jiang YX, Luan S#. (2011) Mechanistic analysis of AKT1 regulation by the CBL-CIPK- PP2CA network. Mol Plant, 4:527-536.

Lan WZ *, Wang W, Wang SM, Li LG, Buchanan BB, Lin HX, Gao JP, Luan S# (2010) A rice high-affinity potassium transporter (HKT) conceals a calcium-permeable cation channel. Proc Natl Acad Sci U S A,107:7089-7094.

Lee SC*, Lan WZ*, Buchanan BB#, Luan S#. (2009) A protein kinase- phosphatase pair interacts with an ion channel to regulate ABA signaling in plant guard cells. Proc Natl Acad Sci U S A, 106:21419-21424.

Lee SC*, Lan WZ*, Kim BG*, Li LG*, Cheong YH, Pandey GK, Lu G, Buchanan BB#, Luan S# (2007) A protein phosphorylation/dephosphorylation network regulates a plant potassium channel. Proc Natl Acad Sci U S A, 104:15959-15964.

Others：

Yang Y*, Tang RJ, Mu B, Ferjani A, Shi J, Zhang H, Zhao F, Lan WZ #, Luan S#. Vacuolar Proton Pyrophosphatase Is Required for High Magnesium Tolerance in Arabidopsis . Int J Mol Sci. 2018 Nov 16;19(11). pii: E3617. doi: 10.3390/ijms19113617.

Yu J, Ge H, Wang X, Tang R, Wang Y, Zhao F, Lan W#, Luan S#, Yang L#. Overexpression of Pyrabactin Resistance-Like Abscisic Acid Receptors Enhances Drought, Osmotic, and Cold Tolerance in Transgenic Poplars. Front Plant Sci. 2017 Oct 13;8:1752.

Zhang C*, Li H*, Wang J, Zhang B, Wang W, Lin H, Luan S, Gao J#, Lan W #. The Rice High-Affinity K+ Transporter OsHKT2;4 Mediates Mg2+ Homeostasis under High-Mg2+ Conditions in Transgenic Arabidopsis. Front Plant Sci. 2017, 24;8:1823.

Ji R, Zhou L, Liu J, Wang Y, Yang L, Zheng Q#, Zhang C, Zhang B, Ge H, Yang Y, Zhao F, Luan S, Lan W#. Calcium-dependent protein kinase CPK31 interacts with arsenic transporter AtNIP1;1 and regulates arsenite uptake in Arabidopsis thaliana. PLoS One. 2017 Mar 15;12(3):e0173681.

Yu J, Li H, Peng Y, Yang L, Zhao F, Luan S#, Lan W#. A survey of the pyrabactin resistance-like abscisic acid receptor gene family in poplar. Plant Signal Behav. 2017 Aug 3;12(8):e1356966.

Liu J, Fu S, Yang L, Luan M, Zhao F, Luan S#, Lan W#. Vacuolar SPX-MFS transporters are essential for phosphate adaptation in plants. Plant Signal Behav. 2016;11(8):e1213474.

Yu J, Yang L#, Liu X, Tang R, Wang Y, Ge H, Wu M, Zhang J, Zhao F, Luan S#, Lan W#. Overexpression of Poplar Pyrabactin Resistance-Like Abscisic Acid Receptors Promotes Abscisic Acid Sensitivity and Drought Resistance in Transgenic Arabidopsis. PLoS One. 2016;11(12):e0168040.

Luan S#, Lan WZ, Lee SC. (2009) Potassium nutrition, sodium toxicity, and calcium signaling: connections through the CBL-CIPK network. Current Opinion in Plant Biology, 12:339-346.

Lan WZ, Wang PYT, Hill CE. (2006) Modulation of hepatocellular swelling-activated K+ currents by phosphoinositide pathway-dependent protein kinase C. American Journal of Physiology-Cell Physiology, 291:93-103.

Lan WZ, Abbas H, Lam HD, Lemay AM, Hill CE. (2005) Contribution of a time-dependent and hyperpolarization-activated chloride conductance to currents of resting and hypotonically shocked rat hepatocytes. American Journal of Physiology-Gastrointestinal and Liver Physiology, 288:G221-G229.

Lan WZ, Abbas H, Lemay AM, Briggs MM, Hill CE. (2005) Electrophysiological and molecular identification of hepatocellular volume-activated K+ channels. Biochimica Et Biophysica Acta-Biomembranes, 1668:223-233.

专著：

Wu W, Wang Y, Lee S, Lan WZ, Luan S. Regulation of Ion Channels by the Calcium Signaling Network in Plant Cells. Demidchik V and Maathuis F (eds.) Ion channels and plant stress responses. Signaling and communication in plants. 2010, Springer-Verlag Berlin Heidelberg.

全国各地天气预报查询

上海市

云南省

云南省

云南省

云南省

云南省