罗冬根

北京大学生命科学学院研究员、中国认知科学学会化学感知分会会长

罗冬根，北京大学生命科学学院研究员，北京大学麦戈文脑研究所研究员，北京大学定量生物学中心研究员，北京大学-清华大学生命联合中心研究员、中国认知科学学会化学感知分会会长。

人物经历

教育经历

2003年中国科学院上海生理研究所理学博士

1999年华东师范大学理学硕士

1996年华东师范大学理学学士

工作经历

2013年7月北京大学研究员

2009-2013年约翰霍普金斯大学医学院神经科学系助理研究员(Research Associate, Faculty)

2003-2009年约翰霍普金斯大学医学院神经科学系博士后

2024年12月，中国认知科学学会化学感知分会会长。

研究方向

神经生物学

主要成就

2023年10月，北大生命科学学院、麦戈文脑研究所、定量生物学中心、生命科学联合中心罗冬根研究员团队发现“一细胞，两递质，两视觉功能”的神经机制。

代表性论文

1. Xiao N, Xu S, Li ZK, Tang M, Mao R, Yang T, Ma SX, Wang PH, Li MT, Sunikumar A, Rouyer F, Cao LH, and Luo DG. (2023) A single photoreceptor splits perception and entrainment by cotransmission. Nature (in press).

2. Tang M, Cao LH, Yang T, Ma SX, Jing BY, Xiao N, Xu S, Leng KR, Yang D, Li MT, Luo DG.(2022) An extra-clock ultradian brain oscillator sustains circadian timekeeping. Science Advances 8, eabo5506.

3. Luo DG, Silverman D, Frederiksen R, Adhikari R, Cao LH, Oatis JE, Kono M, Cornwall MC, and Yau KW. (2020) Apo-opsin and its dark constitutive activity across retinal cone subtypes. Current Biology 30: 4921-4931.

4. Wu F, Deng B, Xiao N, Wang T, Li Y, Wang R, Shi K, Luo DG, Rao Y, Zhou C. (2020) A neuropeptide regulates fighting behavior in Drosophila melanogaster. Elife e54229.

5. Zhou Y, Cao LH, Sui XW, Guo XQ, and Luo DG. Mechanosensory circuits coordinate two opposing motor actions in Drosophila feeding. Science Advances 2019, 5: eaaw5141.

6. Li MT, Cao LH, Xiao N, Tang M, Deng B, Yang T, Yoshii T, and Luo DG. Hub-organized parallel circuits of central circadian pacemaker neurons for visual photoentrainment in Drosophila. Nature Communications 2018, 9: 4247.

7. Cao LH, Yang D, Wu W, Zeng X, Jing BY, Li MT, Qin SS, Tang C, Tu Y, and Luo DG. Odor-evoked inhibition of olfactory sensory neurons drives olfactory perception in Drosophila. Nature Communications 2017, 8: 1357.

8. Yue WW, Frederiksen R, Ren X, Luo DG, Yamashita T, Shichida Y, Cornwall MC, Yau KW. Spontaneous activation of visual pigments in relation to openness/closedness of chromophore-binding pocket. eLife, 2017, 6. pii: e18492.

9. Cao LH, Jing BY, Yang D, Zeng X, Shen Y, Tu Y and Luo DG. Distinct signaling of Drosophila chemoreceptors in olfactory sensory neurons. Proc. Natl. Acad. Sci. USA, 2016, 113, E902-E911.

10. Cao LH, Luo DG and Yau KW. Light responses of primate and other mammalian cones. Proc. Natl. Acad. Sci. USA, 2014, 111, 2752-2757.

11. Luo DG*, Yue WWs, Ala-Laurila P and Yau KW*. Activation of visual pigments by light and heat. Science, 2011, 332, 1037-1032. (*Co-corresponding Authors)

12. Fu Y*, Kefalov VJ*, Luo DG*, Xue T* and Yau KW. Quantal noise from human red cone pigment. Nature Neuroscience, 2008, 11, 565-571. (*Equal Contributions)

13. Luo DG, Xue T, and Yau KW. How vision begins: an odyssey. Proc. Natl. Acad. Sci. USA, 2008, 105, 9855-9862.

14. Su CY, Luo DG, Terakita A, Schichida Y, Liao HW, Kazmi MA, Sakamar TP and Yau KW. Parietal-eye phototransduction components and their potential evolutionary implications. Science, 2006, 311, 11617-11621.

15. Luo DG and Yau KW. Rod sensitivity of neonatal mouse and rat. J. Gen. Physiol., 2005, 126, 263-269.

16. Fu YB, Zhong HN, Wang MH, Luo DG, Liao HW, Maeda H, Hattar S, Frishman LJ and Yau KW. Intrinsically photosensitive retinal ganglion cells detect light with a Vitamin A-based photopigment, melanopsin. Proc. Natl. Acad. Sci. USA, 2005, 102, 10339-10344.

17. Huttl S, Michalakis S, Seeliger M, Luo DG, Acar N, Geiger H, Hudl K, Mader R, Haverkamp S, MOser M, Pfeifer A, Gerstner A, Yau KW and Beil M. Impaired channel targeting and retinal degeneration i mice lacking the cyclic nucleotide-gated channel subunit CNGB1. J. Neurosci., 2005, 25, 130-138.

18. Luo DG, Li GL and Yang XL. Zn2+ modulates light responses of color-opponent bipolar and amacrine cells in the carp retina. Brain Res. Bull., 2002, 58, 461-468.

19. Luo DG and Yang XL. Suppression by zinc of transient OFF responses of carp amacrine cells to red light is mediated by GABAa receptors. Brain Res., 2002, 958, 222-226.

20. Luo DG and Yang XL. Zn2+ differentially modulates signals from red- and short-wavelenth-sensitive cones to horizontal cells in carp reitna. Brain Res., 2001, 900, 95-102.

21. Xu HP, Luo DG and Yang XL. Signals from cone photoreceptors to L-tyoe horizontal cells are differntially modulated by low calcium in carp retina. Eur. J. Neurosci., 2001, 13, 1411-1419.

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