钟世安,男,中共党员,博士(后),中南大学教授,博士生导师,天然产物及药物合成化学团队负责人,“531人才工程”计划资助。早年留学澳大利亚昆士兰大学,一直从事天然药效活性成分的分离与纯化、修饰与改性,现代分离科学与工程等方面的教学和科研。先后主持国家自然科学基金、国家农业成果转化基金、国家863计划项目、国家科技部科技攻关项目8项,省部级重点计划项目、省自然科学基金5项,各类企业合作项目15项。在《Analytical Chemistry》、《Chemical Communications》、《Journal of Cleaner Production》、《Food chemistry》、《International Journal of Biological Macromolecules》、《Chemistry - A European Journal》、《ACS Sensors》、《Materials Science and Engineering: C》、《Journal of hazard materials》、《Electrochimica Acta》、等国内外SCI刊物上共发表论文180余篇,现为《Journal of Chromatography A》、《Analytical Chemistry》、《International Journal of Biological Macromolecules》等国际权威刊物审稿专家;教育部科技进步奖评审专家,国家自然科学基金、中国博士后科学基金、教育部博士点基金、新教师基金评审专家。出版教材5本,专著3本,申请国家发明专利40余项,获国家授权专利35项。
人物经历
1996-1999
中南工业大学化学系硕士研究生,获硕士学位
1999-2002
中南大学化学化工学院博士研究生, 获博士学位
2001-2003 中南大学化学化工学院讲师
2003-2005
中南大学材料科学与工程学院参加博士后科研工作
2011- 中南大学化学化工学院教授,博士生导师
研究方向
1、天然药物化学
2、纳米靶向性控释药物
3、现代分离科学与技术
4、高分子医用材料
研究生招生方向
1、制药工程(硕士研究生、博士研究生招生)
2、生物化工(硕士研究生招生)
主要贡献
在研课题
发明专利
申请国家发明专利40余项,获国家授权专利35项,以第一发明人的专利情况:
论文
共发表ESI等高水平论文120余篇,近来以第一作者或通讯作者发表的部分代表性论文有:
1.Synthesis of Size-tunable Hollow Polypyrrole Nanostructures and Their Assembly into Folate Targeting and pH-responsive Anti-cancer Drug Delivery [J]. European: Chemistry - A European Journal, 2017, 68,17279-17289
2. Molecularly imprinted polymers based on zeolite imidazolate framework-8 for selective removal of 2,4-dichlorophenoxyacetic acid[J]. Colloids and Surfaces A-physicochemical and engineering aspects, 2019, 570 :244–250
3. An improved synthesis ofthe5‑HT1A receptor agonist Eptapirone free base[J]. Chemical Papers, 2019, DOI:10.1007/s11696-019-00685-1
4. Polymethacrylic acid encapsulated TiO2 nanotubes for sustained drug release and enhanced antibacterial activities[J]. New J. Chem. 2019, DOI: 10.1039/c8nj04568b
5. Molecularly imprinted polymers fabricated using Janus particle-stabilized Pickering emulsions and charged monomer polymerization[J]. New J. Chem., 2018, 42, 7355
6. Molecularly imprinted polymers fabricated via Pickering emulsions stabilized solely by food-grade casein colloidal nanoparticles for selective protein recognition [J]. Analytical and Bioanalytical Chemistry, 2018, 410:3133–3143
7.An effective and convenient synthesis of cordycepin from adenosine [J]. Chemical Papers, 10.1007/s11696-017-0
8.Assembling of stimuli-responsive tumor targeting polypyrrole nanotubes drug carrier system for controlled release[J]. Materials Science and Engineering: C , 2018, 89: 316~327
9.A Pt/TiO2 Nanotube Array Electrode for Glucose Detection and Its Photoelectrocatalysis Self-Cleaning Ability [J]. J. Electrochem. Soc, 2017, 164(2): B66-B73
10. Multifunctional Halloysite Nanotubes for Targeted Delivery and Controlled Release of Doxorubicin In-Vitro and In-Vivo Studies [J]. Nanotechnology, 2017, 28: 37-42
11. Nanoscale trifunctional bovine hemoglobin for fabricating molecularly imprinted polydopamine via Pickering emulsions-hydrogels polymerization [J]. Colloids and Surfaces B: Biointerfaces, 2017, 159C: 131-138
12. Hydrophilic surface molecularly imprinted naringin prepared via reverse atom transfer radical polymerization with excellent recognition ability in a pure aqueous phase [J]. RSC Advances, 2017, 7(45): 28082-28091
13. Interconnectivity of macroporous molecularly imprinted polymers fabricated by hydroxyapatite-stabilized Pickering High internal phase emulsions-hydrogels for the selective recognition of protein [J]. Colloids and Surfaces B: Biointerfaces, 2017, 155: 142-149
14. Combination of adsorption by functionalized halloysite nanotubes and encapsulation by polyelectrolyte coatings for sustained drug delivery [J]. RSC Advances, 2016, 6(59): 54463-54470
15. The synthesis of temperature-sensitive molecularly imprinted film on novel support beads and its application for bovine serum albumin separation [J]. Colloids and Surfaces A, 2016, 504: 367-375
16. Bio-inspired magnetic molecularly imprinted polymers based on Pickering emulsions for selective protein recognition [J]. NEW JOURNAL OF CHEMISTRY, 2016, 40(10): 8745-8752
17. Halloysite-based dopamine-imprinted polymer for selective protein capture [J]. JOURNAL OF SEPARATION SCIENCE, 2016, 39(12): 2431-2437
18. Graphene oxide as a sacrificial material for fabricating molecularly imprinted polymers via Pickering emulsion polymerization [J]. RSC ADVANCES, 2016, 6(78): 74654-74661
19. Functionalization of halloysite nanotubes by enlargement and hydrophobicity for sustained release of analgesic [J]. Colloids and Surfaces A, 2015, 487: 154-16
20. Fabrication and evaluation of protein imprinted polymer based on magnetic halloysite nanotubes [J]. RSC Advances, 2015, 2015(5): 61-68
21. One-step synthesis of boronic acid group modified silica particles by the aid of epoxy silanes [J]. Applied Surface Science, 2015, 351: 353–357
22. Water-compatible halloysite-imprinted polymer by Pickering emulsion polymerization for the selective recognition of herbicides [J]. Journal of Separation Science, 2015, 38: 1365
23. One-pot preparation of boronic acid and PEG bi-functionalized silica particles for separation and purification of catecholamine from rat serum [J]. New Journal of Chemistry, 2015, 39: 8848-8854
24. A novel molecularly imprinted materials based on magnetic halloysite nanotubes for rapid enrichment 2, 4- dichlorophenoxyacetic acid in water [J]. Journal of hazardous materials, 2014, 276: 58-65
25. A novel self-cleaning, non-enzymatic glucose sensor working under a very low applied potential based on a Pt nanoparticle-decorated TiO2 nanotube array electrode [J]. Electrochimica Acta,, 2014, 115: 269-276
26. Efficient conversion of myricetin from Ampelopsis grossedentata extracts and its purification by MIP- SPE [J]. Journal of Chromatography B, 2014, 945-946: 39-45
27. Preparation and characterization of molecularly imprinted organic–inorganic hybrid materials by sol–gel processing for selective recognition of ibuprofen [J]. Journal of sol-gel science and technology, 2013, 66(1): 59–67
28. Silica particles coated with azobenzene-containing photoresponsive molecule-imprinted skin layer [J]. Colloid and Polymer Science, 2013, 291(9): 92049–2059
29. Synthesis of novel photoresponsive molecularly imprinted polymer microspheres with special binding properties [J]. Journal of Applied Polymer Science, 2013, 130(15): 869-876
30. Design and computational simulation of stimuli-responsive polymer by sol-gel for selective recognition of (4-chloro-2-methylphenoxy)acetic acid [J]. Polymer international, 2012, 61: 1778–1785
31. Dendritic polymers based on poly(ethylene glycol)-co-poly(glycolic acid)-co-methacrylate and 2.0 G-polyamidoamine- metharylamide: Design, Characterization, and in vitro degradation, and drug release properties [J]. Polymer Degradationand Stability, 2012, 97: 234-241
32. Synthesis of molecularly imprinted organic-inorganic hybrid azobenzene materials by sol gels for radiation induced selective recognition of 2,4-Dichlorophenoxy- acetic acid [J]. Radiation Physical Chemistry, 2011, 80(2): 130-135
33. Computer Simulation and Preparation of Molecularly Imprinted Polymer Membranes with Chlorogenic Acid as Template [J]. Polymer international, 2011, 60: 592-598
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